Search on:
RECQ3 PROTEIN
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Werner Syndrome Helicase
Descriptor
Spanish
:
Helicasa del Síndrome de Werner
Descriptor
Portuguese
:
Helicase da Síndrome de Werner
Synonyms
English
:
RECQ3 Protein
RECQL2 Protein
Werner Syndrome ATP-Dependent Helicase
Werner Syndrome RecQ-Like Helicase
Helicase, Werner Syndrome
Werner Syndrome ATP Dependent Helicase
Werner Syndrome RecQ Like Helicase
Tree Number:
D08.811.277.040.025.159.249.500
D08.811.277.352.335.375.875
D08.811.277.352.365.290.500
D08.811.399.340.249.500
D12.776.157.687.750
D12.776.660.720.750
Definition
English
:
A DNA-dependent helicase and 3'-5' exonuclease. It has 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang and binds preferentially to DNA
substrates
containing alternate secondary structures, such as replication forks and HOLLIDAY JUNCTIONS.
Mutations
in the WRN gene are associated with
WERNER SYNDROME.
History Note
English
:
2017
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56469
Unique Identifier:
D000071657
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS